Showing all 22 results
Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs and the technologies for studying and engineering stem cells.
The book will educate and decode the role of vitamins, essential fatty acids and other nutraceuticals on skin health and their tremendous impact to the current needs of the skin care industry. Focus on conditions, as acne, dermatitis, dry scaly skin or alopecia will provide a comprehensive knowledge of the relationship of nutrition and skin as well as the current attempts in nutritional or dermatological research. It will stimulate food professionals to brainstorm for new products and opportunities that will target the emerging antiaging and wellness trends and modern consumer needs.
In The Aptamer Handbook, leading scientists from academia as well as biotech and pharma companies introduce the revolutionary concept of designing RNA and DNA oligonucleotides with novel functions by in vitro selection. These functions comprise high affinity binding (aptamers), catalytic activity (ribozymes and deoxyribozymes) or combinations of binding and catalytic properties (aptazymes).
Derived from the best-selling classic text originated by Lubert Stryer and continued by John Tymoczko and Jeremy Berg, Biochemistry: A Short Course focuses on the major topics taught in a one-semester biochemistry course. With its short chapters and relevant biological and clinical examples, this text shows biochemistry as a part of students’ everyday lives. Offering the same signature writing style and physiological emphasis as the full-length text, this briefer book focuses on the major topics by eliminating details of enzyme mechanisms and organic chemistry, and by removing extraneous and advanced topics.
Corynebacterium glutamicum was discovered in Japan in 1956 as a natural glutamate producer. Its “microbial factory” qualities, such as its physiological plasticity and robust catalytic functionalities, have since facilitated the development of efficient production processes for amino acids, nucleotides and vitamins.
This monograph illustrates how the information gleaned from complete genome sequencing allows the rational engineering of the entire cellular metabolism and how systems biology permits the further optimization of C.
Goodbye, genetic blueprint. . . . The first book for general readers ?on the game-changing field of epigenetics. The burgeoning new science of epigenetics offers a cornucopia of insights—some comforting, some frightening. For example, the male fetus may be especially vulnerable to certain common chemicals in our environment, in ways that damage not only his own sperm but also the sperm of his sons. And it’s epigenetics that causes identical twins to vary widely in their susceptibility to dementia and cancer.
For four decades, this extraordinary textbook played a pivotal role in the way biochemistry is taught, offering exceptionally clear writing, innovative graphics, coverage of the latest research techniques and advances, and a signature emphasis on physiological and medical relevance. Those defining features are at the heart of this edition.
Written as a textbook with an online laboratory manual for students and adopting faculties, this work is intended for non-science majors / liberal studies science courses and will cover a range of scientific principles of food, cooking and the science of taste and smell. Chapters include: The Science of Food and Nutrition of Macromolecules; Science of Taste and Smell; Milk, Cream, and Ice Cream, Metabolism and Fermentation; Cheese, Yogurt, and Sour Cream; Browning; Fruits and Vegetables; Meat, Fish, and Eggs; Dough, Cakes, and Pastry; Chilies, Herbs, and Spices; Beer and Wine; and Chocolate, Candy and Other Treats.
This book is a comprehensive survey of the dialogue between pagans, Jews, and Christians in the Roman empire up to the time when Constantine declared himself a Christian. Each chapter is written by a distinguished scholar and is devoted to a single text or group of texts with the aim of identifying the probable audience, the literary milieu, and the circumstances that led to this form of writing.
Chromium exists in nature as complexes of two stable oxidation states – trivalent chromium(III) and hexavalent chromium(VI). Although trivalent chromium is required in trace amounts for sugar and lipid metabolism in humans and its deficiency may cause a disease called chromium deficiency; hexavalent chromium is toxic and carcinogenic. As chromium compounds were used in dyes and paints and the tanning of leather, these compounds are often found in soil and groundwater at abandoned industrial sites, now needing environmental cleanup and remediation.
The Bioinorganic Chemistry of Chromium: From Biochemistry to Environmental Toxicology takes a critical look at what the biochemical data indicate about chromium’s role in the body and the biological mechanisms of its toxicology. Topics covered include:
What do we know about the biochemical roles and mechanisms of chromium?
Is chromium an essential element in the mammalian diet?
Is chromium(III) effective as a nutraceutical, a therapeutic agent, and as a supplement in animal feed?
What is the biochemistry behind the toxicology of chromium(III) and chromium(VI):the mechanisms of metabolism, genetic and epigenetic effects, and disruption of cell signalling?
What are the current chromium(VI) policies and positions from regulatory agencies?
The Bioinorganic Chemistry of Chromium: From Biochemistry to Environmental Toxicology is an important contribution to the bioinorganic and trace element biochemical fields which will find a place on the bookshelves of bioinorganic chemists, biochemists, inorganic chemists, toxicologists, nutritionists and regulatory affairs professionals.
During the course of the last two decades, the health effects of tea and its catechins have been docmnented in nmnerous scientific studies and the scientific basis of these effects has been elaborated.
This best-selling undergraduate textbook provides an introduction to key experimental techniques from across the biosciences. It uniquely integrates the theories and practices that drive the fields of biology and medicine, comprehensively covering both the methods students will encounter in lab classes and those that underpin recent advances and discoveries.
Leading researchers, from the Novartis group that pioneered Gleevec/Glivec™ and around the world, comprehensively survey the state of the art in the drug discovery processes (bio- and chemoinformatics, structural biology, profiling, generation of resistance, etc.) aimed at generating PTK inhibitors for the treatment of various diseases, including cancer. Highlights include a discussion of the rationale and the progress made towards generating "selective" low molecular-weight kinase inhibitors; an analysis of the normal function, role in disease, and application of platelet-derived growth factor antagonists; and a summary of the factors involved in successful structure-based drug design.
Perspectives in Supramolecular Chemistry will relate recent developments and new exciting approaches in supramolecular chemistry. In supramolecular chemistry, our aim is to understand the molecular chemistry beyond the covalent bond the series will concentrate on goal-orientated supramolecular chemistry.
Our knowledge of the chemistry of selenium and tellurium has seen significant progress in the last few decades. This monograph comprises contributions from leading scientists on the latest research into the synthesis, structure and bonding of novel selenium and tellurium compounds. It provides insight into mechanistic studies of these compounds and describes coordination chemistry involving selenium and tellurium containing ligands. Contributions also describe the theoretical and spectroscopic studies of selenium and tellurium compounds.
From the groundbreaking partnership of W. H. Freeman and Scientific American comes this one-of-a-kind introduction to the science of biology and its impact on the way we live. In Biology for a Changing World, two experienced educators and a science journalist explore the core ideas of biology through a series of chapters written and illustrated in the style of a Scientific American article. Chapters don’t just feature compelling stories of real people—each chapter is a newsworthy story that serves as a context for covering the standard curriculum for the non-majors biology course.
Dienes and polyenes are an extremely important group of chemicals in the investigation of different types of syntheses. Dienes and Polyenes are found in a large number of natural and man-made products including such natural products as terpenes, cholesterol, Vitamin A, and many essential oils, as well as many polymers and rubber products. In recent years the organometallic complexes of these compounds have been found to play an important role in synthesis. This volume is an invaluable reference source for researchers in academia and industry in organic and natural product chemistry and materials science.
The first book of a two volume treatise on protein purification methods and applications, this title covers both traditional and recently developed techniques for initial purification, which is fundamental to any investigation of protein chemistry. The theory and basic principles of each technique are discussed, including initial planning, clarification and extraction, concentration of the extract, structure-based separation, activity-based purification, and gel permeation chromatography. Problem areas and solutions are highlighted at each stage, making this book equally valuable to novice researchers and more experienced protein biochemists who will find it a reliable and readily accessible bench manual.
Comprehensive, concise, and up-to-date, Harper’s is unrivaled in its ability to clarify the link between biochemistry and the molecular basis of health and disease.The Twenty-Eighth Edition has undergone sweeping changes – including a conversion to full-color artwork and the substantial revision and updating of every chapter – all to reflect the latest advances in knowledge and technology and to make the text as up-to-date and clinically relevant as possible. Combining outstanding full-color illustrations with integrated coverage of biochemical diseases and clinical information, Harper’s Illustrated Biochemistry offers an organization and clarity not found in any other text on the subject.S
The Biochemistry of Cell Signalling deals in depth with the principles of cell signalling, concentrating on structure and mechanism. It will serve as a reliable map through the maze of cell signalling pathways and help the reader understand how malfunctions in these pathways can lead to disease. The book is divided into four parts. Part 1 describes the machinery of signal transduction starting with the properties of signals, receptors (including receptor activation), regulators, and the molecules that link receptor and regulator.
Animal Endo-SiRNAs: Methods and Protocols presents a variety of approaches to investigate endo-siRNAs. These include protocols applicable to study short RNAs expressed at a low level and model systems that are particularly suitable to investigate specific aspects of endo-siRNAs, their synthesis, their genomics or regulatory role. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Animal Endo-SiRNAs: Methods and Protocols contains practical tips that are absent in standard lab manuals.
Graduate students and medical students have different needs in their learning of biochemistry. Medical students often complain that their biochemistry courses do not focus on clinical relevance. This book, while not a reference book or a dissertation on all aspects of biochemistry, selects the most clinically relevant material that every clinician should know, and presents it in a way that enables the student to quickly see and understand clinical biochemistry as a conceptual whole.
Showing all 22 results