Biotechnology

by Richard G Burns , Richard P Dick , Language: English

The need to understand the biological processes that are important for essential aquatic and terrestrial ecosystem function has prompted much research into the field of ecological enzymology. This book presents the two broad areas of application in a compilation of reviews by 21 international experts in their respective fields. The first explores enzymatic activities to assess the processes or mechanisms that operate in a given system, such as the rhizosphere, plant leaves and shoots, soil surfaces, and biofilms.

by Song Li , Nicolas L Heureux , Jennifer Elisseeff , Language: English

Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs and the technologies for studying and engineering stem cells.

by Chris C Shaw , Language: English

Conventional computed tomography (CT) techniques employ a narrow array of x-ray detectors and a fan-shaped x-ray beam to rotate around the patient to produce images of thin sections of the patient. Large sections of the body are covered by moving the patient into the rotating x-ray detector and x-ray source gantry. Cone beam CT is an alternative technique using a large area detector and cone-shaped x-ray beam to produce 3D images of a thick section of the body with one full angle (360 degree or 180 degree plus detector coverage) rotation.

by H T Banks , H T Tran , Language: English

Through several case study problems from industrial and scientific research laboratory applications, Mathematical and Experimental Modeling of Physical and Biological Processes provides students with a fundamental understanding of how mathematics is applied to problems in science and engineering. For each case study problem, the authors discuss why a model is needed and what goals can be achieved with the model.Exploring what mathematics can reveal about applications, the book focuses on the design of appropriate experiments to validate the development of mathematical models.

by Franz Hillenkamp , Jasna Peter-Katalinic , Language: English

This authoritative book on MALDI MS, now finally available in its second edition and edited by one of its inventors, gives an in–depth description of the many different applications, along with a detailed discussion of the technology itself. Thoroughly updated and expanded, with contributions from key players in the field, this unique book provides a comprehensive overview of MALDI MS along with its possibilities and limitations. The initial chapters deal with the technology and the instrumental setup, followed by chapters on the use of MALDI MS in protein research (including proteomics), genomics, glycomics and lipidomics.

by Stefan Behme , Language: English

Structured like a textbook, the second edition of this reference covers all aspects of biopharmaceutical manufacturing, including legal and regulatory issues, production facility design, and quality assurance, with a focus on supply chain management and regulations in emerging markets and cost control.
The author has longstanding industrial expertise in biopharmaceutical production and years of experience teaching at universities. As such, this practical book is ideal for use in academia as well as for internal training within companies.

by Hideaki Yukawa , Masayuki Inui , Language: English

Corynebacterium glutamicum was discovered in Japan in 1956 as a natural glutamate producer. Its “microbial factory” qualities, such as its physiological plasticity and robust catalytic functionalities, have since facilitated the development of efficient production processes for amino acids, nucleotides and vitamins.
This monograph illustrates how the information gleaned from complete genome sequencing allows the rational engineering of the entire cellular metabolism and how systems biology permits the further optimization of C.

by Dmitry V Bavykin , Frank C Walsh , Royal Society of Chemistry (Great Britain , Language: English

A unique compilation of data from a wide range of chemical and spectroscopic instrumentation and their integration into nanostructure characterisation.

by Richard F Wilson , Language: English

Advances in genomics and biotechnology are enabling quantum leaps in the understanding of soybean molecular biology. The problems that face the soybean industry also are diversifying and escalating on a global scale. Designing Soybeans for the 21st Century outlines current and emerging barriers in the global soybean market, principally: 1) long-term ability to sustain production to meet continued growth in demand for soybean and soybean products; 2) governmental and legislative policies; 3) global access to advances in soybean technology; and 4) customer and consumer trends in the use of soybean products.

by Keith J Gooch , Chris J Tennant , Language: English

Animal Cell Culture nimal cell culture began in 1912 when Alexis Carrel grew bits of chick heart A in vitro by placing them into a drop of horse plasma. When the plasma clotted, it formed a solid surface into which the heart cells explanted. Left unattended, these cells died within several days. By regularly feeding the grow­ ing cells with aqueous extracts of whole chick embryos and periodically sub­ dividing them, Carrel was able to maintain the cells for extended periods. From these initial experiments, cell culture has expanded into an important component of biological research and commercial production.

by Levon Khachigian , Language: English

In the post-genomic era we have, at our fingertips, an incredible array of genomic sequences from a multitude of complex organisms. There remains, however, the critical need to understand the precise roles individual genes play in complex biological milieu.

by Sang Yup Lee , Language: English

Systems biology is changing the way biological systems are studied by allowing us to examine the cell and organism as a whole. Systems biotechnology allows optimal design and development of upstream to downstream bioprocesses by taking a systems-approach.

by Brian W Metcalf , Susan Dillon , Language: English

This work presents a comprehensive contemporary framework for approaching target validation in drug discovery. It begins with a detailed description of new enabling technologies, including aptamers, RNA interference, functional genomics, and proteomics.

by Christof Niemeyer , Language: English

Nanotechnology is the key technology of the 21st century. The possibility to exploit the structures and processes of biomolecules for novel functional materials, biosensors, bioelectronics and medical applications has created the rapidly growing field of nanobiotechnology.Designed as a broad survey of the field, this book combines contributions from bioorganic and bioinorganic chemistry, molecular biology, materials science and bioanalytics to fathom the full scope of current and future developments.I

by Paul Harrison , C Gardiner , Ian L Sargent , Language: English

Interest in the role of extracellular vesicles (microvesicles and exosomes) is expanding rapidly. It is now apparent that far from being merely cellular debris, these vesicles play a key role in cell-to-cell communication and signaling. Moreover, they are significantly elevated in a number of diseases. This raises the question of their direct role in pathogenesis as well as their possible use as biomarkers.This book stems from the first international meeting on "Microvesicles and Nanovesicles in Health and Disease" held at Magdalen College, Oxford, in 2010.

by Konstantina S Nikita , Institute of Electrical and Electronics Engineers , Language: English

"Handbook of Biomedical Telemetry describes the main components of a typical biomedical telemetry system as well as its technical challenges. Author K. S. Nikita addresses technologies for biomedical sensing and design of biomedical telemetry devices with special emphasis on powering/integration issues and materials for biomedical telemetry applications. Covering biomedical telemetry devices, biosensor network topologies and standards, clinical applications, wearable and implantable devices, and the effects on the mobile healthcare system, this compendium is a must have for professional engineers as well as researchers and graduate students"–Provided by publisher.

by Jeremy Dale , Malcolm von Schantz , Nick Plant , Language: English

The latest edition of this highly successful textbook introduces the key techniques and concepts involved in cloning genes and in studying their expression and variation.The new edition features:Increased coverage of whole-genome sequencing technologies and enhanced treatment of bioinformatics.Clear, two-color diagrams throughout.A dedicated website including all figures.Noted for its outstanding balance between clarity of coverage and level of detail, this book provides anexcellent introduction to the fast moving world of molecular genetics.

by Gillian Cockerill , Stephen Reed , Language: English

This textbook provides a unique, pocket-sized, self-directed study guide to fluid, electrolyte and acid base homeostasis for undergraduate biomedical science, pharmacology, medical and allied health students. It details the chemical (mostly ionic) composition of body fluids, explains how abnormalities arise, what laboratory tests can be used to identify and analyze the cause of these disorders and shows how normality can be achieved to maintain health.

by John M Lachin , Language: English

Biostatistical Methods focuses on the assessment of risks and relative risks on the basis of clinical investigations. It develops basic concepts and derives biostatistical methods through both the application of classical mathematical statistical tools and more modern likelihood–based theories.

by Gerd-Joachim Krauss , Dietrich H Nies , Language: English

The first stand-alone textbook for at least ten years on this increasingly hot topic in times of global climate change and sustainability in ecosystems.Ecological biochemistry refers to the interaction of organisms with their abiotic environment and other organisms by chemical means. Biotic and abiotic factors determine the biochemical flexibility of organisms, which otherwise easily adapt to environmental changes by altering their metabolism. Sessile plants, in particular, have evolved intricate biochemical response mechanisms to fit into a changing environment.

by National Research Council (U.S.). Committee on Research at the Intersection of the Physical and Life Sciences , Language: English

Traditionally, the natural sciences have been divided into two branches: the biological sciences and the physical sciences. Today, an increasing number of scientists are addressing problems lying at the intersection of the two. These problems are most often biological in nature, but examining them through the lens of the physical sciences can yield exciting results and opportunities. For example, one area producing effective cross-discipline research opportunities centers on the dynamics of systems.

by Beth A Goins , MD William T Phillips , Language: English

The first resource of its kind, this book covers cutting-edge research on the use of nanoparticles for in vivo diagnostic medical imaging and therapy. It discusses a variety of nanoparticles, including quantum dots, carbon nanotubes, dendrimers, gold nanoshells, metal nanorods, micelles, liposomes, polymers, MRI iron oxide particles, and microbubbles. Examples in the book include multifunctional nanoparticles that designed for multimodality imaging and simultaneous diagnostic and therapy (theranostic) applications.

by Luis Rueda , Language: English

Microarray Image and Data Analysis: Theory and Practice is a compilation of the latest and greatest microarray image and data analysis methods from the multidisciplinary international research community. Delivering a detailed discussion of the biological aspects and applications of microarrays, the book:Describes the key stages of image processing, gridding, segmentation, compression, quantification, and normalizationFeatures cutting-edge approaches to clustering, biclustering, and the reconstruction of regulatory networksCovers different types of microarrays such as DNA, protein, tissue, and low- and high-density oligonucleotide arraysExamines the current state of various microarray technologies, including their availability and affordabilityExplains how data generated by microarray experiments are analyzed to obtain meaningful biological conclusionsAn essential reference for academia and industry, Microarray Image and Data Analysis: Theory and Practice provides readers with valuable tools and techniques that extend to a wide range of biological studies and microarray platforms.

by Thomas R Peltier , Language: English

This book illustrates how to develop the related standards, procedures, and guidelines for implementing policy. Each chapter provides advice on the structural mechanics of the various documents as well as an example of each form. This new edition updates material on the concept of responsibilities that reflects the general nature of the individuals responsible. Standards and procedures are also updated to reflect the work done in the field during 2002 with additional examples. ISO 17799 is used to identify possible standards that enterprises can create.