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Statistical methods are a key ingredient in providing data–based guidance to research and development as well as to manufacturing. Understanding the concepts and specific steps involved in each statistical method is critical for achieving consistent and on–target performance.
Written in response to reader requests for a short, “to the point” text that clearly summarizes the most important chemical elements of therapeutically relevant drug classes, Essentials of Foye’s Principles of Medicinal Chemistry is a concise, quick-reference source of reliable information in the field. Derived from the highly regarded Foye’s Principles of Medicinal Chemistry, this focused text provides an essential understanding of drug action and demonstrates its practical application to today’s pharmacy practice.H
In The Aptamer Handbook, leading scientists from academia as well as biotech and pharma companies introduce the revolutionary concept of designing RNA and DNA oligonucleotides with novel functions by in vitro selection. These functions comprise high affinity binding (aptamers), catalytic activity (ribozymes and deoxyribozymes) or combinations of binding and catalytic properties (aptazymes).
The inspiration for this book came from an American Carbon Society Workshop entitled "Carbon Materials for Advanced Technologies" which was hosted by the Oak Ridge National Laboratory in 1994. Chapter 1 contains a review of carbon materials, and emphasizes the structure and chemical bonding in the various forms of carbon, including the four allotropes diamond, graphite, carbynes, and the fullerenes. In addition, amorphous carbon and diamond films, carbon nanoparticles, and engineered carbons are discussed.
This book is the latest addition to the highly regarded food colloid series and is of relevance to those working and researching in food science and surface and colloid science.
The chemical study of insects has been growing for four decades, and with it an interest in how insects make their pheromones, hormones, defensive secretions, venoms, pigments and surface coverings. By investigating the biosynthesis of insects, one can gain a greater insight into the structure and function of insect compounds, into ways of disrupting biosynthetic reactions in pest species and how these pathways evolved.
A plain–English guide to one of the toughest science courses around Organic chemistry is rated among the most difficult courses that students take and is frequently the cause of washout among pre–med, medical, and nursing students. This book is an easy–to–understand and fun reference to this challenging subject. It explains the principles of organic chemistry in simple terms and includes worked–out problems to help readers get up to speed on the basics.
Helping you keep pace with rapid developments in the field, Textile Sizing documents the rapidly changing scenario in textile processing and research in sizing. The authors analyze new fibers, spinning methods, and weaving techniques affecting textile production and studies the impact of fiber properties, yarn quality, sizing processes and materials, and chemical and mechanical phenomena on efficient textile manufacturing and development.
Stirring is one of the most important operations in process technology. No chemical exists that has non been submitted to a mixing process during its synthesis. Furthermore, stirring is important for the pharmaceutical and food industries, too.
A modern introduction to the subject taking a unique integrated approach designed to appeal to both science and engineering students. Covering a broad spectrum of topics, this book includes numerous up–to–date examples of real materials with relevant applications and a modern treatment of key concepts. The science bias allows this book to be equally accessible to engineers, chemists and physicists. ∗ Carefully structured into self–contained bite–sized chapters to enhance student understanding ∗ Questions have been designed to reinforce the concepts presented ∗ Includes coverage of radioactivity ∗ Relects a rapidly growing field from the science perspective
Using new instrumentation and experimental techniques that allow scientists to observe chemical reactions and molecular properties at the nanoscale, the authors of Surface and Nanomolecular Catalysis reveal new insights into the surface chemistry of catalysts and the reaction mechanisms that actually occur at a molecular level during catalysis.
Learn the key concepts of basic and clinical neurology with a unique practice-oriented approachFor more than two decades, Clinical Neurology has helped students, residents, and clinicians understand the link between basic neuroscience and current approaches in diagnosis and treatment. Distinguished by its practice-oriented approach to neurology based on the patients’ presenting symptoms, this full-color resource delivers the clearest and most efficient introduction to the field available today.Every chapter of this edition has been updated, and in many cases nearly completely rewritten to maintain the emphasis on the practical aspects of neurology while discussing the scientific underpinnings.
This journey through the fascinating world of molecular topology focuses on catenanes, rotaxanes and knots, their synthesis, properties, and applications and the theory of interlocking and interpenetrating molecules. Nearly one hundred years of progress have passed since Willstätter′s speculative vision of a molecule consisting of two interlinked rings.
This book addresses the most recent advances in the transport of proteins across a variety of biological membranes. In addressing this topic, this volume includes several new twists not previously addressed in the literature. In the last few years, the study of protein translocation has been revolutionized by the availability of structural information on many of the components and complexes involved in the process. Unlike earlier books written on protein translocation, this volume considers these advances.
Bestselling author David Agus unveils the brave new world of medicine, one in which we can take control of our health like never before and doctors can fine-tune strategies and weapons to prevent illness.In his first bestseller, The End of Illness, David Agus revealed how to add vibrant years to your life by knowing the real facts of health. In this book, he builds on that theme by showing why this is the luckiest time yet to be alive, giving you the keys to the new kingdom of wellness.Medicine is undergoing rapid change.
This book provides an interdisciplinary review of one of the great unsolved mysteries that has fascinated scientists for over 150 years: the origin of chirality in biomolecules. It was Pasteur who first initiated the search for a deterministic theory to explain the ‘handedness’ of biomolecules. His theory, that a ‘dissimetric’ force was involved, was correct in essence but he never saw the fruits of his labour. Current thinking tells us that asymmetry in the universe has its origins in the forces that unfolded after the Big Bang and, more specifically, the weak force.
Providing a comprehensive introduction with the necessary background material to make it accessible for a wide scientific audience, Kinetics of Phase Transitions discusses developments in domain-growth kinetics. This book combines pedagogical chapters from leading experts in this area and focuses on incorporating various experimentally relevant effects―such as disorder, strain fields, and wetting surfaces―into studies of phase ordering dynamics.
Many creatures use adhesive polymers and structures to attach to inert substrates, to each other, or to other organisms. This is the first major review that brings together research on many of the well-known biological adhesives dealing with bacteria, fungi, algae, and marine and terrestrial animals.
The ever increasing demands for environmental and consumer protection are a continuous challenge for research, development and regulation of crop protection chemicals. This book exclusively documents thirty invited lectures held at the 10th IUPAC International Congress on the Chemistry of Crop Protection in August 2002. These edited contributions take the form of reviews and presentations of original research results. They cover fundamental aspects of biology, chemistry, biochemistry and molecular biology of disease, weed and insect control agents, as well as economic issues, aspects in production, formulation and application, and recent regulatory developments in environmental and consumer protection.
This book is about elements that kill. Mercury, arsenic, antimony, lead, and thallium can be lethal, as many a poisoner knew too well. Emsley explores the gruesome history of these elements and those who have succumbed to them in a fascinating narrative that weaves together stories of true crime, enduring historical mysteries, tragic accidents, and the science behind it all. The colourful cast includes ancient alchemists, kings, leaders, a pope, several great musicians, and a motley crew of murderers.
Dienes and polyenes are an extremely important group of chemicals in the investigation of different types of syntheses. Dienes and Polyenes are found in a large number of natural and man-made products including such natural products as terpenes, cholesterol, Vitamin A, and many essential oils, as well as many polymers and rubber products. In recent years the organometallic complexes of these compounds have been found to play an important role in synthesis. This volume is an invaluable reference source for researchers in academia and industry in organic and natural product chemistry and materials science.
The Logic of Chemical Synthesis The title of this three-part volume derives from a key theme of the book-the logic underlying the rational analysis of complex synthetic problems. Although the book deals almost exclusively with molecules of biological origin, which are ideal for developing the fundamental ideas of multistep synthetic design because of their architectural complexity and variety, the approach taken is fully applicable to other types of carbon-based structures. Part One outlines the basic concepts of retrosynthetic analysis and the general strategies for generating possible synthetic pathways by logical reduction of molecular complexity.
This long-awaited, greatly-expanded new edition of a best-selling guide offers an encyclopedic and systematic collection of useful synthetic methodology, including tens of thousands of reactions and synthetic transformations. The first edition has been reviewed in the professional journals as "clearly…the first choice for researchers seeking information on synthetic transformations." And as "useful to anyone who must do organic synthesis, especially those whose focus is not strictly organic chemistry.
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