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Electrochemistry plays an important role in preserving our cultural heritage. For the first time this has been documented in the present volume. Coverage includes both electrochemical processes such as corrosion and electroanalytical techniques allowing to analyse micro- and nanosamples from works of art or archaeological finds.
Dienes and polyenes are an extremely important group of chemicals in the investigation of different types of syntheses. Dienes and Polyenes are found in a large number of natural and man-made products including such natural products as terpenes, cholesterol, Vitamin A, and many essential oils, as well as many polymers and rubber products. In recent years the organometallic complexes of these compounds have been found to play an important role in synthesis. This volume is an invaluable reference source for researchers in academia and industry in organic and natural product chemistry and materials science.
In this most comprehensive reference source for the development, production and therapeutic application of antibodies, Volume I contains general chapters presenting established technologies and clinical applications. Volume II provides a look at emerging technologies, new therapeutic concepts, and clinical studies. The third volume features detailed and specific information about each currently approved type of antibody, including the clinical data. A must-have resource for academic researchers, decision makers in industry and healthcare professionals in the clinic.
This book is devoted to the application of advanced signal processing on event-related potentials (ERPs) in the context of electroencephalography (EEG) for the cognitive neuroscience. ERPs are usually produced through averaging single-trials of preprocessed EEG, and then, the interpretation of underlying brain activities is based on the ordinarily averaged EEG. We find that randomly fluctuating activities and artifacts can still present in the averaged EEG data, and that constant brain activities over single trials can overlap with each other in time, frequency and spatial domains.
With the rise of advanced computerized data collection systems, monitoring devices, and instrumentation technologies, large and complex datasets accrue as an inevitable part of biomedical enterprise. The availability of these massive amounts of data offers unprecedented opportunities to advance our understanding of underlying biological and physiological functions, structures, and dynamics.
Biosignal Processing: Principles and Practices provides state-of-the-art coverage of contemporary methods in biosignal processing with an emphasis on brain signal analysis.
We have known for over a thousand years that the brain underlies behavioral expression, but effective scientific study of the brain is only very recent. Two things converge in this book: a great respect for neuroscience and its many variations, and a sense of investigation and inquiry demythologized. Think of it as foraging for coherence.
The ethics of creating-or declining to create-human beings has been addressed in several contexts: debates over abortion and embryo research; literature on "self-creation"; and discussions of procreative rights and responsibilities, genetic engineering, and future generations. Here, for the first time, is a sustained, scholarly analysis of all of these issues-a discussion combining breadth of topics with philosophical depth, imagination with current scientific understanding, argumentative rigor with accessibility.
You’re about to discover how to develop a self-discipline that will make you more successful than you ever could imagine! Sure, you could be talented. You could be born with the ”right” parents or win on horses. However, with the right willpower you get anything you want, without luck and without any special benefits. Did Tim Ferris get a contract with the first publisher he asked? No. With the second? No. He asked over twenty publishers before he got his book published and now it is a world wide best seller.
In this illuminating volume, Robert P. Abelson delves into the too-often dismissed problems of interpreting quantitative data and then presenting them in the context of a coherent story about one’s research. Unlike too many books on statistics, this is a remarkably engaging read, filled with fascinating real-life (and real-research) examples rather than with recipes for analysis. It will be of true interest and lasting value to beginning graduate students and seasoned researchers alike. The focus of the book is that the purpose of statistics is to organize a useful argument from quantitative evidence, using a form of principled rhetoric.
For two decades, Swine in the Laboratory: Surgery, Anesthesia, and Experimental Techniques has been the most respected practical technical guide for medical and veterinary researchers using swine as experimental animals. Extensively updated and expanded since the publication of the second edition in 2007 and now sponsored by the American College of Laboratory Animal Medicine (ACLAM), it continues to be the most authoritative source of scientific and technical information on the use of domestic and miniature swine in research.A
A groundbreaking book showing the link between Adverse Childhood Experiences (ACEs) and adult illnesses such as heart disease, autoimmune disease, and cancer—Childhood Disrupted also explains how to cope with these emotional traumas and even heal from them.
Your biography becomes your biology. The emotional trauma we suffer as children not only shapes our emotional lives as adults, it also affects our physical health, longevity, and overall wellbeing. Scientists now know on a bio-chemical level exactly how parents’ chronic fights, divorce, death in the family, being bullied or hazed, and growing up with a hypercritical, alcoholic, or mentally ill parent can leave permanent, physical “fingerprints” on our brains.
When we as children encounter sudden or chronic adversity, excessive stress hormones cause powerful changes in the body, altering our body chemistry. The developing immune system and brain react to this chemical barrage by permanently resetting our stress response to “high,” which in turn can have a devastating impact on our mental and physical health.
Donna Jackson Nakazawa shares stories from people who have recognized and overcome their adverse experiences, shows why some children are more immune to stress than others, and explains why women are at particular risk. Groundbreaking in its research, inspiring in its clarity, Childhood Disrupted explains how you can reset your biology—and help your loved ones find ways to heal.
A full-color review of the clinically important aspects of microbiologyIncludes more than 20 case studiesThe twenty-sixth edition of Jawetz, Melnick & Adelberg’s Medical Microbiology delivers a concise, up-to-date overview of the roles microorganisms play in human health and illness. Linking fundamental principles with the diagnosis and treatment of microbial infections, this classic text has been updated throughout to reflect the tremendous expansion of medical knowledge that has taken place since the last edition published.
This book intends to be neither a complete survey of the field nor an exhaustive source of references. For these purposes, the use of the extensive compilation "Experimental Immunochemistry" by E. A. KABAT and M. M. MAYER (1962) or the excellent methodological textbook, "Methods in Immunology", by D. H. CAMPBELL, J. S. GARVEY, E. E. CREMER and D. H. SUSSDORF (1963), or the quite comprehensive series "Methods in Immunology and Immunochemistry" by C. A. WILLIAMS and M.
The Biochemistry of Cell Signalling deals in depth with the principles of cell signalling, concentrating on structure and mechanism. It will serve as a reliable map through the maze of cell signalling pathways and help the reader understand how malfunctions in these pathways can lead to disease. The book is divided into four parts. Part 1 describes the machinery of signal transduction starting with the properties of signals, receptors (including receptor activation), regulators, and the molecules that link receptor and regulator.
Now fully revised and updated, Bioethics: An Anthology, 3rd edition, contains a wealth of new material reflecting the latest developments. This definitive text brings together writings on an unparalleled range of key ethical issues, compellingly presented by internationally renowned scholars. * The latest edition of this definitive one-volume collection, now updated to reflect the latest developments in the field * Includes several new additions, including important historical readings and new contemporary material published since the release of the last edition in 2006 * Thematically organized around an unparalleled range of issues, including discussion of the moral status of embryos and fetuses, new genetics, neuroethics, life and death, resource allocation, organ donations, public health, AIDS, human and animal experimentation, genetic screening, and issues facing nurses * Subjects are clearly and captivatingly discussed by globally distinguished bioethicists * A detailed index allows the reader to find terms and topics not listed in the titles of the essays themselves
Combining the Sanskrit words "ayur" (life) and "veda" (knowledge), Ayurveda is an ancient Indian practice for living that dates back thousands of years. Ayurveda promotes a mind-consciousness-body balance that, when in perfect alignment, results in improved health, outlook, and attitude. This is the optimal guide for families interested in Ayurveda, with information on:- The history of Ayurvedic medicine in India- Discovering individual "doshas," or personality types- Incorporating Ayurvedic foods into your everyday diet- Yoga and exercise techniques for each "dosha"- Meditation and relaxation tips for the whole familyPacked with information and guidance, plus more than twenty-five Ayurvedic recipes for meals and snacks that your whole family will love, this guide is the perfect resource for transitioning into a healthy, balanced way of living!
Addressing the challenge of serious infection, especially MRSA, in hospitals, in the community, and in animals, Maggie Tisserand focuses on the scientifically proven effects of antibacterial essential oils, and their usefulness in managing infection, including the ‘superbug’. She profiles the key essential oils – tea tree, manuka and thyme – covering everything from habitat, chemistry and commercial uses to the latest scientific research that proves their effectiveness against bacterial infection, and how they should be used.
Small Animal Medical Diagnosis, Third Edition takes a problem-oriented approach to clinical diagnosis and outlines core information necessary to effectively evaluate the major medical problems in dogs and cats. The text starts by defining problems caused by disease and proceeds to integrate the history, physical examination, and diagnostic modalities into a logical approach designed to assist with the medical management of patients. The new edition continues to serve as a vital tool in accurate and appropriate diagnosis for small animal veterinarians, emergency and critical care veterinarians, and veterinary students.
The book introduces a radically new way of thinking about information and the important role it plays in living systems. It opens up new avenues for exploring how cells and organisms change and adapt, since the ability to detect and respond to meaningful information is the key that enables them to receive their genetic heritage, regulate their internal milieu, and respond to changes in their environment. It also provides a way of resolving Descartes’ dilemma by explaining the workings of the brain in non-mechanical terms that are not tainted by spiritual or metaphysical beliefs.
Animal Endo-SiRNAs: Methods and Protocols presents a variety of approaches to investigate endo-siRNAs. These include protocols applicable to study short RNAs expressed at a low level and model systems that are particularly suitable to investigate specific aspects of endo-siRNAs, their synthesis, their genomics or regulatory role. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Animal Endo-SiRNAs: Methods and Protocols contains practical tips that are absent in standard lab manuals.
The analysis and sorting of large numbers of cells with a fluorescence-activated cell sorter (FACS) was first achieved some 30 years ago. Since then, this technology has been rapidly developed and is used today in many laboratories.A Springer Lab Manual Review of the First Edition: "This is a most useful volume which will be a welcome addition for personal use and also for laboratories in a wide range of disciplines. Highly recommended."
In 1960 Sir Frank Macfarlane Burnet received the Noble Prize in Physiology and Medicine. He titled his Nobel Lecture “Immunological Recognition of Self” emphasizing the central argument of immunological tolerance in “How does the vertebrate organism recognize self from nonself in this the immunological sense―and how did the capacity evolve.” The concept of self is linked to the concept of biological self identity. All organisms, from bacteria to higher animals, possess recognition systems to defend themselves from nonself.
The second edition of this popular book has been extensively rewritten and up-dated. As well as being an essential introductory text for beginners to this field, it is also of interest to more experienced workers wishing to refresh their knowledge. ; ; Im
This book presents a contemporary review of the field of pain therapeutics, including the historical medicines which still dominate standard of care treatments, as well as the new mechanisms and combinations/reformulations that have dominated the regulatory approvals over the last decade. In addition, it provides a deep review of the key biological mechanisms currently under investigation for their utility into the treatment of pain, such as ion channels, opiates and others.Additional discussion highlights the current challenges of pain research, covering a range of topics from difficulties in identifying new targets and pre-clinical models to the current regulatory and commercial challenges.
Showing 937–960 of 1008 results