Showing 961–984 of 1008 results
In recent years, interest in the preparation and characterization of nanostructured materials has grown due to their distinctive properties and potential technological applications. Nanoscale materials represent a new realm of matter and offer widespread possibilities for contributions to science and technology.
The Logic of Chemical Synthesis The title of this three-part volume derives from a key theme of the book-the logic underlying the rational analysis of complex synthetic problems. Although the book deals almost exclusively with molecules of biological origin, which are ideal for developing the fundamental ideas of multistep synthetic design because of their architectural complexity and variety, the approach taken is fully applicable to other types of carbon-based structures. Part One outlines the basic concepts of retrosynthetic analysis and the general strategies for generating possible synthetic pathways by logical reduction of molecular complexity.
Food and Industrial Bioproducts and Bioprocessing describes the engineering aspects of bioprocessing, including advanced food processing techniques and bioproduct development. The main focus of the book is on food applications, while numerous industrial applications are highlighted as well. The editors and authors, all experts in various bioprocessing fields, cover the latest developments in the industry and provide perspective on new and potential products and processes. Challenges and opportunities facing the bioproduct manufacturing industry are also discussed.
This thorough and multidisciplinary overview of childrearing illustrates and stands on two foundational principles: that the importance of parenting is immense, and that it is undervalued. The Critical Role of Parenting in Human Development surprises readers with the realization that the way we were parented in childhood impacts nearly every aspect of our lives. Based in part on cutting-edge research using MRI and fMRI technologies demonstrating that the brains of those traumatized in childhood are essentially different, the book explains that our brain development during our earliest years and in the womb is fundamental to the lives we lead.I
This is the first book to collate and synthesize the recent burgeoning primary research literature on dog behaviour, evolution, and cognition. The author presents a new ecological approach to the understanding of dog behaviour, demonstrating how dogs can be the subject of rigorous and productive scientific study without the need to confine them to a laboratory environment. Dog Behaviour, Evolution, and Cognition starts with an overview of the conceptual and methodological issues associated with the study of the dog, followed by a brief description of their role in human society-almost a third of human families share their daily life with the dog! An evolutionary perspective is then introduced with a summary of current research into the process of domestication.
This book aims to provide a comprehensive examination of the field of molecular chaperone inhibition and its application to pharmaceutical research. With several small molecule inhibitors in oncology clinical development, there is clearly intense interest in the chaperones as a molecular target. Filling a significant gap in the market by providing a detailed comparison of discovery programs across the industry, this text will find broad interest among researchers in the field of molecular chaperone pharmaceutical research, oncology research, and medicinal chemistry.A
DC Dutta’s Textbook of Obstetrics is the eighth edition of this comprehensive and highly illustrated textbook. Thoroughly revised and updated, the book spans 42 chapters, incorporating new material and the latest advances in the field of obstetrics. New topics in this edition include prenatal genetic counselling, screening and diagnosis, whilst progress in technology is recognised with the inclusion of Doppler studies, MR images, microphotographs, data graphs and laparoscopic images. This highly detailed book is formatted for ease of reference, with expanded contents and index, and colour coded headings and key points at the end of every chapter, highlighting essential information.
The thoroughly updated Fifth Edition of Pediatric Neuroimaging is a highly illustrated text-reference that describes and illustrates the full range of pediatric disorders diagnosable by modern neuroimaging. Covering the diagnosis of brain, spinal, and head and neck disorders in the pediatric patient, the text is rooted in the principle that the proper interpretation of studies requires the acquisition of high-quality images and an understanding of the basic concepts of neuroembryology, normal development, and pathophysiology.
Mentalizing – the ability to understand oneself and others by inferring mental states that lie behind overt behaviour – develops within the context of attachment relationships. It is crucial to self-regulation and constructive, intimate relationships, both of which are impaired in personality disorders because of sensitivity to losing mentalizing at times of anxiety and attachment stress. Loss of mentalizing leads to interpersonal and social problems, emotional variability, impulsivity, self-destructive behaviours, and violence.
Following in the footsteps of the previous two volumes, this third volume of the Alexander Discipline, focusing on unusual and difficult cases, demonstrates through the presentation of complete patient records how these principles can be used to achieve beautiful, functional, and stable results even in patients requiring creative treatment planning and treatment mechanics. In the situations presented in this book, there is no one right answer to the problem, and the orthodontist must have the confidence and relevant knowledge to formulate the treatment plan most suitable for each patient.
Authors: Kleine, Bernhard, Rossmanith, Winfried G.Comprehensive overview on the endocrinology of humans and animals with emphasis on hormone biochemistry, hormone physiology, hormone receptors, endocrine organs, regulatory circuit and regulation of endocrine rhythmsShort characteristics covering the most important facts are given for all hormonesCovers endocrinology of vertebrates as well as of invertebratesThis book focuses on hormones, and on how they are produced in very diverse regions of the body in humans and animals.
Authors: Katz, Martin M.Identifies weaknesses in evaluating new drugs Presents two new models for the evaluation of putative antidepressantsAppeals to clinicians, investigators, drug companies and patientsThis brief guide takes current clinical trial protocols to task and replaces them with a contemporary framework for improving next-generation antidepressants and their underlying science. Innovative models are based on a nuanced, neurologically-informed understanding of drug mechanisms and the component cognitive, mood, and behavioral aspects of depression.
As drug development shifts over time to address unmet medical needs and more targeted therapies are developed, previously unseen pharmacological or off-target effects may occur in treatment. Designed to provide practical information for the bench toxicologic pathologist working in pharmaceutical drug research, Toxicologic Pathology: Nonclinical Safety Assessment presents a histopathologic description of lesions observed during drug development and discusses their implication in the drug development process.
Divided into two sections, the book systematically assists pathologists in making a determination as to the origin and potential importance of a lesion and its relevance for assessing human risk. The first section includes eight “concept” chapters to orient pathologists in areas that are important for effective interaction with other pathologists as well as the many non-pathologists involved in drug development. The second section is made up of organ-based chapters, each including light microscopic and electron microscopic descriptions of pathological lesions, differential diagnoses, biological consequences, pathogenesis, mechanism of lesion formation, and the expected clinical pathology correlates.
This volume presents critical information―both published and unpublished and gained through personal experience―to improve the quality of drug safety evaluation and to expedite and improve the efficiency of the process. This book is crafted to assist students, residents, and toxicologic pathologists in their early career phase by serving as a resource that can effectively be used as a ready reference next to the microscope. In addition, more experienced pathologists will find this volume to be invaluable during their assessments. The book is also a valuable reference for toxicologists to assist in understanding compound-related pathological findings and to provide background for working on a range of toxicological problems.
A picture is worth a thousand words, and the goal of this atlas is to better understand patellofemoral conditions through pictures. Hence the reason we have decided to publish this book, which is a collection of the finest images of patellofemoral joint surgery, supplied by world renowned specialists in Knee surgery. All the images, footnotes and summaries are compiled in order to convey a simple understanding of this complex problem. This is a very practical book, aimed at the general orthopedic surgeon and also those that specialize in surgery of the knee.
This guide offers the reader a comprehensive theraputic approach for the evaluation and treatment of myofascial pain and musculoskeletal dysfunction. This manual serves as a quick reference for clinically relevant items that pertain to the identification and management of trigger points. The first section of the book covers the therapy and research regarding the Myofascial Trigger Point Syndrome. Treatment methods and techniques are also covered in a comprehensive step-by-step format. The second section includes the most important muscles that tend to have a higher incidence of the myofascial involvement.
Scientists have attributed more than 40 percent of the failures in new drug development to poor biopharmaceutical properties, particularly water insolubility. Issues surrounding water insolubility can postpone, or completely derail, important new drug development. Even much-needed reformulation of currently marketed products can be significantly affected by these challenges.Water Insolubility is the Primary Culprit in over 40% of New Drug Development FailuresThe most comprehensive resource on the topic, this second edition of Water Insoluble Drug Formulation brings together a distinguished team of experts to provide the scientific background and step-by-step guidance needed to deal with solubility issues in drug development.
These properties have been taken advantage of in exploration of potential applications including in ch- ical sensors, light-emitting devices, and ?eld-effect transistors. Many efforts have been devoted to synthesizing new conjugated polymers and oligomers in an effort to increase their processibility, optimize the desirable properties, and explore new properties.
Updated and invigorated, “Understanding Sports Massage, Second Edition, ” provides readers with an understanding of the fundamental theory and practical basis for using sports massage to keep athletes in top shape, recover from injuries, and improve performance. Like the successful first edition, “Understanding Sports Massage” is ideal for sport professionals and students in sports massage training programs. The book illustrates and explains massage techniques in detail and describes the procedures involved in conducting effective sports massage sessions, including determining goals, organizing the session, and choosing and applying techniques.
The third edition of Handbook of Marriage and the Family describes, analyzes, synthesizes, and critiques the current research and theory about family relationships, family structural variations, and the role of families in society. This updated Handbook provides the most comprehensive state-of-the art assessment of the existing knowledge of family life, with particular attention to variations due to gender, socioeconomic, race, ethnic, cultural, and life-style diversity. The Handbook also aims to provide the best synthesis of our existing scholarship on families that will be a primary source for scholars and professionals but also serve as the primary graduate text for graduate courses on family relationships and the roles of families in society.
A nutritional whodunit that takes readers from Greenland to Africa to Israel, The Queen of Fats gives a fascinating account of how we have become deficient in a nutrient that is essential for good health: The fatty acids known as omega-3s. Writing with intelligence and passion, Susan Allport tells the story of these vital fats, which are abundant in greens and fish, among other foods. She describes how scientists came to understand the role of omega-3s in our diet, why commercial processing has removed them from the food we eat, and what the tremendous consequences have been for our health.
Psychology in the work context 5e is an introductory text for students of industrial and organisational psychology. The book provides a comprehensive conceptual framework for understanding work behaviour and relationships at work and equips the student with a theoretical framework form which to analyse issues in the work place.
This review volume integrates the advances in cancer biology, molecular imaging techniques and imaging probes for visualization and quantitative measurement of anatomical, functional, and molecular profiles of cancer. The volume also presents a comprehensive summary of the state-of-the-art technology in molecular imaging probe design and applications in radionuclide (PET and SPECT), magnetic resonance (MR), optical (fluorescence, Raman, photoacoustic), ultrasound, CT, and multimodality imaging. Bringing together the fundamentals of molecular imaging, and the basic principles of each molecular imaging modality in this volume, readers’ understanding in this field is further enhanced.
Have you ever imagined what a truly great health system could look like?Over the past six years, author Mark Britnell has worked in 60 countries – covering eight-tenths of the world’s GDP – with hundreds of government, public and private healthcare organisations. With chapters on 25 different countries, including Brazil, China and the USA, his practical, succinct guide to the world’s major health systems explores what lessons can be drawn from each to improve health worldwide.This insightful and informative exploration of health systems around the world will give you a truly global health perspective.
The Oxford American Handbook of Oncology is the essential reference for medical students, residents, and clinical oncologists seeking a current, portable resource on the delivery of sophisticated cancer care. Chapters focus on the immediate information needs in clinical decision making including treatment choices. Algorithms, best practice guidelines, highlighted tables, and targeted lists of landmark references enhance the concise text. For the second edition biologic therapies and therapeutic regimens and options and clinical trial information have been rigorously updated throughout.
Showing 961–984 of 1008 results